The Next Evolution of Clinical Trial Data Collection is Here

Do you remember Double Data Entry (DDE)? Subject data was captured on paper (Case Report Forms), then sent to the study sponsor where it was manually entered into a database (twice!) to identify entry errors. Site queries were manually created and sent to the Research Coordinator for clarification. Inefficient and error prone to say the least.

Then came Remote Data Entry (RDE) where subject data is manually entered into an online data collection system (Electronic Case Report Forms) by the Research Coordinator. Fortunately, this improved the quality of data collected using programmed edit checks that cleaned data at the source. It also significantly reduced the cycle time to arrive at database lock. Unfortunately, it also placed a significant administrative burden on the Coordinator performing the data entry.

Currently, doctors and nurses participating in research efforts is a regulatory requirement in the US and across the globe, and many are asking the same question: How can we streamline the clinical trial data collection process and alleviate administrative burdens on our healthcare providers?

Today, the next evolution in clinical trial data collection is: Zero Data Entry (ZDE™). This leverages cutting edge technology to capture the required subject data without tedious manual data entry into online eCRFs. Continued technological advances in direct data capture from EHRs, voice recognition, AI-driven text analytics, and IoMT (Internet of Medical Things) are enabling this drive towards ZDE™.